Ryuugamine Mikado is a boy who longs for the exciting life of the big city. At the invitation of his childhood friend Masaomi, he transfers to a school in Ikebukuro. Masaomi has warned him about people he doesn't want to cross in the city: a champion fighter, an informant, and a mysterious gang called "Dollars." Nervous from Masaomi's stories, Mikado witnesses an urban legend on his first day in the city, the Headless Rider astride a black motorcycle. From then on, the existence of supernatural cases and a gang called the Yellow Turbans will rise to the surface, and Ikebukuro will pushed to the breaking point.